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Impact of EDCTP-supported activities on policy and practice

Unnecessary delay or failure to translate research findings into policy and practice prevents research from achieving maximum public health benefit. Therefore, EDCTP is very intentional in promoting translation of policy-relevant research results into policy and practice.

Celebrating 20 years of impact through equitable partnerships

The European & Developing Countries Clinical Trials Partnership was established in 2003. This year, we will be celebrating 20 years of supporting equitable European-African research collaborations that have been, and still are, developing new and improved interventions against infectious diseases in sub-Saharan Africa. We invite you to join our Eleventh EDCTP Forum in Paris, France on 7-10 November 2023 and celebrate this momentous occasion with us.

Case studies

As part of the 8th edition of the Science Summit around the 77th United Nations General Assembly (UNGA77), EDCTP organised the session ‘Funding research for impact: strengthening the role of science and evidence-based 


policymaking’. During this session, case studies were presented on advancing the production and usage of reliable research evidence in addressing unmet medical needs, especially amongst vulnerable populations in Africa.


Monitoring & evaluation

In line with internationally recognised principles of results-based management, we monitor and evaluate the EDCTP2 programme to report on its operational performance and results. Our monitoring and evaluation approach draws on a ‘theory of change’ model (see figure below) that maps out the route through which our funding generates immediate outputs (such as the published results from clinical trials), outcomes (such as changes in health policy and practice) and impact (improvements in health and wellbeing and economic gain). This approach helps collect and analyse information from our grants and other activities that are of strategic importance, and more importantly to justify good value-for-money investments.


EDCTP investments in R&D

In 435 projects awarded to date.

€814.45 M

Total funding

19 European countries
and 44 African countries

63 countries participate in EDCTP-funded activities:

Participation in EDCTP activities

(indicative amounts based on signed grant agreements and proposals approved for funding)

Cumulative investment to call for proposals by year

Investment to call for proposals by year

Investments in calls for proposals

€155.63 M

€16.85 M

€83.42 M

€112.14 M

€814.45 M

€100.27 M

€255.90 M

€444.04 M

€608.47 M

€720.37 M

€94.08 M

2014

2015

2016

2017

2018

2019

2020

€164.19 M

€188.14 M

Facts & figures

By May 2022, the second EDCTP programme (EDCTP2; 2014-2024) portfolio comprised 435 grants awarded through 60 calls for proposals, representing a total investment of EUR 814 million. Clinical trials supported by EDCTP2 involve international collaborations spanning >60 countries and 350 institutions in Europe and sub-Saharan Africa, with broader global collaboration. Results from these clinical trials have generated pivotal evidence which has informed national and international policy and practice.


Despite substantial investment in the development of new diagnostics, vaccines and drugs for poverty-related diseases, these interventions may not reach their target populations or be used to their full potential. This is particularly the case in sub-Saharan Africa, where health systems are generally not optimal nor adequately prepared for the delivery and uptake of new or improved products and interventions. Therefore, EDCTP is very intentional in promoting translation of policy-relevant research results into policy and practice.


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Unnecessary delay or failure to translate research findings into policy and practice prevents research from achieving maximum public health benefit. Therefore, EDCTP is very intentional in promoting translation of policy-relevant research results into policy and practice.

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Impact of EDCTP-supported activities on policy and practice

Celebrating 20 years of impact through equitable partnerships

The European & Developing Countries Clinical Trials Partnership was established in 2003. This year, we will be celebrating 20 years of supporting equitable European-African research collaborations that have been, and still are, developing new and improved interventions against infectious diseases in sub-Saharan Africa. We invite you to join our Eleventh EDCTP Forum in Paris, France on 7-10 November 2023 and celebrate this momentous occasion with us.

Case studies

As part of the 8th edition of the Science Summit around the 77th United Nations General Assembly (UNGA77), EDCTP organised the session ‘Funding research for impact: strengthening the role of science and evidence-based policymaking’. During this session, case studies were presented on advancing the production and usage of reliable research evidence in addressing unmet medical needs, especially amongst vulnerable populations in Africa.


EDCTP investments in R&D

In 435 projects awarded to date.

€814.45 M

Total funding

Monitoring & evaluation

In line with internationally recognised principles of results-based management, we monitor and evaluate the EDCTP2 programme to report on its operational performance and results. Our monitoring and evaluation approach draws on a ‘theory of change’ model (see figure below) that maps out the route through which our funding generates immediate outputs (such as the published results from clinical trials), outcomes (such as changes in health policy and practice) and impact (improvements in health and wellbeing and economic gain). This approach helps collect and analyse information from our grants and other activities that are of strategic importance, and more importantly to justify good value-for-money investments.


19 European countries
and 44 African countries

63 countries participate in EDCTP-funded activities:

Participation in EDCTP activities

(indicative amounts based on signed grant agreements and proposals approved for funding)

Cumulative investment to call for proposals by year

Investment to call for proposals by year

Investments in calls for proposals

€155.63 M

€16.85 M

€83.42 M

€112.14 M

€814.45 M

€100.27 M

€255.90 M

€444.04 M

€608.47 M

€720.37 M

€94.08 M

2014

2015

2016

2017

2018

2019

2020

€164.19 M

€188.14 M

Facts & figures

By May 2022, the second EDCTP programme (EDCTP2; 2014-2024) portfolio comprised 435 grants awarded through 60 calls for proposals, representing a total investment of EUR 814 million. Clinical trials supported by EDCTP2 involve international collaborations spanning >60 countries and 350 institutions in Europe and sub-Saharan Africa, with broader global collaboration. Results from these clinical trials have generated pivotal evidence which has informed national and international policy and practice.


Despite substantial investment in the development of new diagnostics, vaccines and drugs for poverty-related diseases, these interventions may not reach their target populations or be used to their full potential. This is particularly the case in sub-Saharan Africa, where health systems are generally not optimal nor adequately prepared for the delivery and uptake of new or improved products and interventions. Therefore, EDCTP is very intentional in promoting translation of policy-relevant research results into policy and practice.