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Towards
EDCTP2’s
 objectives

New or improved medical interventions against
poverty-related infectious diseases.

Medical interventions

86%(€395.83M)
of the total EDCTP investment is into grants supporting 82 collaborative clinical studies and clinical trials.

56%(46)
are phase II and III trials of drugs and vaccines which aim to deliver key evidence on safety and ecacy. The phase 3 trials also aim to provide data to support product registration.

12%(10)
of the large-scale clinical studies involve post-license (phase IV) studies with a view to inuencing health policies and practice and optimising the delivery of medical interventions for the wide-range of sub-Saharan health systems and diverse populations.

22%(18)
of studies target pregnant women and newborns. Other key populations are also involved in the studies, such as children (29; 36%) and adolescents
(35; 43 %).

32
Sub-Saharan Africa countries hosts recruitment sites of EDCTP-funded collaborative clinical studies.

Total funding

€447.04 M

In 192 projects awarded by end of 2018

EDCTP’s investment
 in research & development

2014-2018

Portfolio of grants by disease

Note:
A further €23.62M for
43 grants was awarded
to projects on non-
disease-specific topics.

€423.42 M
149 grants

Towards
EDCTP2’s
 objectives

New or improved medical interventions against
poverty-related infectious diseases.

Medical interventions

86%(€395.83M)
of the total EDCTP investment is into grants supporting 82 collaborative clinical studies and clinical trials.

56%(46)
are phase II and III trials of drugs and vaccines which aim to deliver key evidence on safety and ecacy. The phase 3 trials also aim to provide data to support product registration.

12%(10)
of the large-scale clinical studies involve post-license (phase IV) studies with a view to inuencing health policies and practice and optimising the delivery of medical interventions for the wide-range of sub-Saharan health systems and diverse populations.

22%(18)
of studies target pregnant women and newborns. Other key populations are also involved in the studies, such as children (29; 36%) and adolescents
(35; 43 %).

32
Sub-Saharan Africa countries hosts recruitment sites of EDCTP-funded collaborative clinical studies.

Increase cooperation 
with sub-Saharan Africa through capacity building for conducting clinical trials according to ethical principles and regulatory standards

Collaboration and capacity development

30.40 M
is the total grant investment to support 39 projects to strengthen the enabling environment for clinical trials and research in sub-Saharan Africa.

24
sub-Saharan African countries have received EDCTP support for the establishment of functional regulatory systems and capacities for ethical review of clinical research.

23.43 M
has been invested to support preparedness of 6 sub-Saharan African countries in the ght against Ebola
outbreaks.

89
fellowships that focus on the career development of researchers.

42
sub-Saharan African institutions in
28 countries participate in the EDCTP- supported Networks of Excellence: CANTAM (Central Africa), WANETAM (Western Africa), TESA (Southern Africa)
and EACCR (Eastern Africa).

2000
trainees beneted from EDCTP project-related trainings and workshops on
topics such as study protocol, specimen collection, research and administration, Good Clinical Practice and epidemics
preparedness.

Improve coordination alignment and integration of
European National Programmes.

European coordination

30
researchers from sub-Saharan Africa received funding from the ‘Joint WHO-AFRO/TDR/EDCTP Small Grants Scheme for implementation research on infectious diseases of poverty launched in 2017. The call was supported through a partnership between Germany, Sweden and the UK.

€121 M
the total cash received from the European Participating States to the EDCTP programme.

Increase international cooperation with public
and private partners.

External partnerships

16
sub-Saharan African countries are full members of the EDCTP Association. These members have contributed to a total of €1.21 million by end of 2018 through the Participating States’ Initiated Activities (PISIAs) – research activities within the scope of the EDCTP programme that are funded and implemented by one or more member countries.

52
countries participate in EDCTP-funded activities: 36 sub-Saharan African countries and 16 European countries.

279
institutions are involved in EDCTP projects: 173 sub-Saharan African institutions and 106 European institutions.

60%
of the total EDCTP grant value is allocated to sub-Saharan African institutions (€186 million).

Increase interaction with other EU initiatives, including those linked to development assistance.

External partnerships

68
private sector entities are involved in EDCTP projects. By end of 2018 , these organisations have received €49.42 M in grant value.

3
grant consortia were established through an EDCTP call to support health systems/service optimisation research capacities in cooperation with development assistant’. Two of these consortia received funding from international development cooperation
partners (SIDA and USAID).

17
EDCTP African member countries participated in a survey to inform the development of a strategic policy plan for strengthening health research systems capacities of countries in sub-Saharan Africa. This project is a joint initiative between EDCTP and WHO-TDR.

Total funding

€447.04 M

In 192 projects awarded by end of 2018

EDCTP’s investment
 in research & development

2003-2018

Portfolio of grants by disease

Note:
A further €58.01M for 153 grants was awarded to projects on non-disease-specific topics.
*EDCTP grants only
**EDCTP. grants only

€423.42 M
149 grants
€542.04 M
196 grants

By intervention

Note:
A further €110.47M for 246 grants was awarded to projects on non-intervention-specific topics.
*EDCTP grants only